The Lin Lab combines principles from chemistry and engineering to develop foundational methods for observing and controlling biological events in real time. In its emphasis on customizing protein-ligand affinity and reaction kinetics, our approach can be termed "synthetic biochemistry". In particular, we have been pioneering the engineering and use of photoproteins and viral proteases to develop next-generation molecular diagnostics and therapies. Click on each image to learn more about our projects.
Fluorescent protein-based technologies